BIS has been shown to correlate well with brain metabolism and accurately reflects the response of the brain to a variety of hypnotic agents like propofol, midazolam, alfentanil, and the inhaled anaesthetic agents like isoflurane, sevoflurane.Īnaesthetic agents vary in their relative hypnotic and immobilizing potentials. It monitors the unawareness component of balanced anaesthesia, which is a cortical event and produces a single value (number).
The bispectral index (BIS) of electroencephalograph (EEG) being one such effective tool in this armamentarium.
With the reports that the patients might recall events and conversation during the anaesthetised state, considerable efforts have been made to improve the methods of assessing the depth of anaesthesia. A satisfactory general anaesthetic state can be obtained with a balance of hypnotic drugs and analgesic drugs producing hypnosis, analgesia and reflex suppression.
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